Like all medicines, this medicine can cause side effects, although not everybody gets them.
If you experience the following symptoms, contact your doctor immediately:
large-scale skin reactions (rash and itching all over the body), severe swelling of skin or mucous membranes (angiooedema), shortness of breath, a fall in blood pressure with rapid heart beat and sweating. These could be symptoms of severe allergic reactions to insulins and may become life-threatening.
Very common reported side effects
(may affect more than 1 in 10 people)
As with all insulin therapy, the most frequent side effect is hypoglycaemia.
Hypoglycaemia (low blood sugar) means that there is not enough sugar in the blood.
For further information on the side effects of low blood sugar or high blood sugar, see the box at the end of this leaflet.
Common reported side effects
(may affect up to 1 in 10 people)
Skin changes at the injection site
If you inject your insulin too often at the same skin site, fatty tissue under the skin at this site may either shrink (lipoatrophy) or thicken
(lipohypertrophy). Thickening of fatty tissue may occur in 1 to 2 % of patients while shrinking may occur uncommonly. Insulin that you inject in such a site may not work very well. Changing the injection site with each injection may help to prevent such skin changes.
Skin and allergic reactions
3 to 4 % of patients may experience reactions at the injection site (such as reddening, unusually intense pain on injection, itching, hives, swelling or inflammation). They can also spread around the injection site. Most minor reactions to insulins usually resolve in a few days to a few weeks.
Rare reported side effects
(may affect up to 1 in 1,000 people)
- Severe allergic reactions to insulins
Associated symptoms may include large-scale skin reactions (rash and itching all over the body), severe swelling of skin or mucous membranes (angiooedema), shortness of breath, a fall in blood pressure with rapid heart beat and sweating.These could be symptoms of severe allergic reactions to insulins and may become life-threatening.
A marked change (improvement or worsening) in your blood sugar control can disturb your vision temporarily. If you have proliferative retinopathy (an eye disease related to diabetes) severe hypoglycaemic attacks may cause temporary loss of vision.
In rare cases, insulin treatment may also cause temporary build-up of water in the body, with swelling in the calves and ankles.
Very rare reported side-effects
(may affect up to 1 in 10, 000 people)
In very rare cases, dysgeusia (taste disorders) and myalgia (muscular pain) can occur.
Other side effects with frequency not known (frequency cannot be estimated from available data):
Insulin treatment can cause the body to produce antibodies to insulin (substances that act against insulin). Rarely, this may require a change to your insulin dose.