Skip to content
This is a text only leaflet, designed for the visually impaired. Please visit our electronic Medicines Compendium (eMC) website to view the original document which may contain images or tables.

You may be able to get this leaflet in large print, Braille or as an audio CD, call the RNIB Medicine Leaflet line on 0800 198 5000 for more information.

The product code for this leaflet is: PL12063/0071


Boots Rapid Period Pain Relief 342 mg Tablets (Ibuprofen Lysine)

Company Details


1 Thane Road WestBeestonNottinghamNG2 3AA
[view all information leaflets from this company]

Information for the user

Boots Rapid Period Pain Relief 342 mg Tablets (Ibuprofen Lysine)

Read all of this leaflet carefully because it contains important information for you.

This medicine is available without prescription to treat minor conditions. However, you still need to take it carefully to get the best results from it.

Keep this leaflet, you may need to read it again

Ask your pharmacist if you need more information or advice

Go to top of the page

What this medicine is for

This medicine contains Ibuprofen Lysine which belongs to a group of medicines called non-steroidal anti-inflammatory medicines, which act to relieve pain and reduce swelling.

For the relief of period pain and other symptoms such as muscular pain, backache, headache which may accompany your period. It can also be used for rheumatic pain, neuralgia, migraine, dental pain, fever and the symptoms of colds and flu.

Go to top of the page

Before you take this medicine

This medicine can be taken by adults and adolescents (aged 12-18 years old). However, some people should not take this medicine or should seek the advice of their pharmacist or doctor first.

Do not take:

If you have a stomach ulcer, perforation or bleeding stomach, or have had one in the past

If you have had perforation or a bleeding stomach after taking a non-steroidal anti-inflammatory medicine (you may have been sick and it contained blood or dark particles that look like coffee grounds, passed blood in your stools or passed black tarry stools)

If you are allergic to ibuprofen or any other ingredients of the product, aspirin or other non-steroidal anti-inflammatory medicines (you have ever had asthma, runny nose, itchy skin or swelling of the lips, face or throat after taking these medicines)

If you are taking aspirin with a daily dose above 75 mg, or other non-steroidal anti-inflammatory medicines

If you have severe heart, kidney or liver failure

If you are pregnant, and in the last 3 months of pregnancy

Talk to your pharmacist or doctor:

If you have asthma, a history of asthma or other allergic disease, bowel problems, Crohn’s disease, ulcerative colitis

If you have other kidney, heart or liver problems (see above)

If you have a connective tissue disorder such as SLE (Systemic Lupus Erythematosus)

If you are elderly – you may get more side effects (see back of leaflet)

If you are between 12 and 18 years old and you are dehydrated – you may get kidney problems

If you are taking any other painkillers or receiving regular treatment from your doctor

If you have had a stroke, or have heart problems, high blood pressure, diabetes, high cholesterol, or you smoke – see ‘Risk of heart attack or stroke’ below

If you are pregnant, and in the first 6 months of pregnancy

Other important information

Risk of heart attack or stroke: Ibuprofen may increase the risk if you take large amounts for a long time. The risk is small. Take the lowest amount for the shortest possible time to reduce this risk.

Breastfeeding: You can take this medicine.

Woman of childbearing age: If you take this medicine, it may reduce your ability to become pregnant. This effect will be reversed when you stop taking the medicine.

If you take other medicines

Before you take these tablets, make sure that you tell your pharmacist about ANY other medicines you might be using at the same time, particularly the following:

Other painkillers

Aspirin 75 mg (to prevent heart attacks and strokes) – the protection may be reduced when you take ibuprofen

Medicines to thin your blood (e.g. warfarin)

Mifepristone (for termination of pregnancy) – do not take ibuprofen if you have taken mifepristone in the last 12 days

Medicines for depression

Water tablets (diuretics), or medicines to treat high blood pressure, medicines for heart problems

Corticosteroids (for pain and swelling)

Lithium (for bipolar disorder)

Methotrexate (for cancer, psoriasis, or rheumatism)

Zidovudine (for HIV infection)

Quinolone antibiotics (for infections)

Ciclosporin or tacrolimus (given after transplant surgery, or for psoriasis or rheumatism)

If you are unsure about interactions with any other medicines, talk to your pharmacist. This includes medicines prescribed by your doctor and medicine you have bought for yourself, including herbal and homeopathic remedies.

Go to top of the page

How to take this medicine

Check the foil is not broken before use. If it is, do not take that tablet.

Adults, the elderly and adolescents between 12 and 18 years:

Take one or two tablets every 4 hours, if you need to.

Do not take more than 6 tablets in 24 hours.

Take the lowest amount for the shortest possible time to relieve your symptoms.

Swallow each tablet with water.

Do not give to children under 12 years.

Do not take more than the amount recommended above.

If your symptoms worsen at any time, talk to your doctor.

Adults: If your symptoms do not go away within 10 days, talk to your doctor.

Adolescents: (aged 12-18 years old): If your symptoms do not go away within 3 days, talk to your doctor.

Go to top of the page

Possible side effects

Most people will not have problems, but some may get some.

If you are elderly you may be more likely to have some of these side effects.

If you get any of these serious side effects, stop taking the tablets. See a doctor at once:

You are sick and it contains blood or dark particles that look like coffee grounds

Pass blood in your stools or pass black tarry stools

Allergic reactions such as skin rash (which can sometimes be severe and include peeling and blistering of the skin), swelling of the face, neck or throat, worsening of asthma, difficulty in breathing, fast heart rate, low blood pressure, collapse

Meningitis (e.g. stiff neck, fever, disorientation)

If you get any of the following side effects see your pharmacist or doctor:

Uncommon side effects: (may affect up to 1 in 100 people)

Stomach discomfort or pain, feeling sick, indigestion or heartburn


Skin rash, hives, itching

Rare side effects: (may affect up to 1 in 1,000 people)

Diarrhoea, wind, constipation, being sick

Very rare side effects: (may affect less than 1 in 10,000 people)

Stomach ulcer or perforation, worsening of bowel problems such as ulcerative colitis or Crohn’s disease

Kidney problems, which may lead to kidney failure (you may pass more or less urine than normal, have blood in your urine or cloudy urine, or feel breathless, very tired, or weak, have no appetite, or have swollen ankles)

Yellowing of the skin or eyes, pale stools or upper abdominal pain (these may be signs of liver problems)

Tiredness or severe exhaustion, changes in the blood which may cause unusual bruising or unexplained bleeding and an increase in the number of infections that you get (e.g. sore throats, mouth ulcers, flu-like symptoms including fever)

Side effects with an unknown frequency:

Fluid retention, which may cause swelling of the limbs

High blood pressure, heart failure, stroke

There may be a small increased risk of heart attack or stroke if you take large amounts of this medicine for a long time. If you get any symptoms, stop taking the tablets and see your doctor.

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed on this leaflet. You can also report side effects directly via the Yellow Card Scheme at: By reporting side effects you can help provide more information on the safety of this medicine.

Go to top of the page

How to store this medicine

Do not store above 25°C.

Keep this medicine in a safe place out of the sight and reach of children, preferably in a locked cupboard.

Use by the date on the end flap of the carton.

Go to top of the page

What is in this medicine

Each film-coated tablet contains Ibuprofen 200 mg (as Ibuprofen Lysine 342 mg), which is the active ingredient.

As well as the active ingredient, the tablets also contain crospovidone, copovidone, microcrystalline cellulose, magnesium stearate.

The tablet coating contains Opadry II White (containing polyvinyl alcohol, titanium dioxide (E171), macrogol, talc).

The pack contains 8 or 16 white capsule-shaped film-coated tablets.

The tablet is marked with the letters ‘IBL’ on one side.

Go to top of the page

Who makes this medicine

Manufactured for

The Boots Company PLC

by the Marketing Authorisation holder

Wrafton Laboratories Limited
EX33 2DL
Go to top of the page

Leaflet prepared April 2015

If you would like any further information about this medicine, please contact

The Boots Company PLC

Other formats

To request a copy of this leaflet in Braille, large print or audio please call, free of charge:

0800 198 5000 (UK only)

Please be ready to give the following information:

Product name: Boots Rapid Ibuprofen Lysine 342 mg Tablets

Reference number: 12063/0071

This is a service provided by the Royal National Institute of Blind People.

Text size normal Text size at 110% Text size at 120%