Like all medicines, this medicine can cause side effects, although not everybody gets them.
Tell your doctor if you notice any of the following side effects or they get worse:
Common side effects
(may affect up to 1 in 10 people)
Dizziness, low blood pressure (causing dizziness especially on standing), cough, diarrhoea, being sick, headache, impaired kidney function.
Uncommon side effects
(may affect up to 1 in 100 people)
Changes in mood, ‘pins and needles’ or tingling, spinning sensation, taste disturbance, sleep disorder, heart attack or stroke possibly as a result of excessive low blood pressure in high risk patients, palpitations, a racing heart beat, condition causing pain, numbness, coldness and blueness of the fingers (Raynaud’s phenomenon), running nose, feeling sick, stomach pain, indigestion, reduced sexual potency in men, tiredness, weakness or loss of strength, increases in blood urea, creatinine and potassium levels, rash, itching.
Rare side effects
(may affect 1 in 1,000 people)
Decreases in haemoglobin and haematocrit, mental confusion, dry mouth, pale or red irregular raised patches with severe itching (hives), hair loss, psoriasis (itchy scaly pink patches on the elbows, knees, scalp and other parts of the body), high levels of urea and other waste products in the blood due to kidney failure, acute kidney failure, enlarged breasts
in men, increases in blood levels of bilirubin, decreases in blood levels of sodium, syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Very rare side effects
(may affect up to 1 in 10,000 people, including isolated reports)
Reduced production of blood cells by the bone marrow, lymph node disease – enlargement of lymph nodes, autoimmune disease, changes in the numbers and types of your blood cells (anaemia, thrombocytopenia, eosinophilia, leucocytosis, leucopenia, neutropenia, agranulocytosis, haemolytic anaemia). If you notice increased bruising, nosebleeds, sore throats, infections, excessive tiredness, breathlessness on exertion or abnormal paleness of the skin, you should tell your doctor who may want you to have a blood test, low blood sugar levels, narrowing of the airways, sinusitis, inflammation or infection of the lungs due to an allergy (allergic alveolitis or eosinophilic pneumonia), inflammation of the liver (hepatitis) or pancreas, swelling of the intestines (intestinal angioedema), liver failure, an abnormally low or non production of urine, sweating, serious blistering skin disease (pemphigus), severe rash involving reddening, peeling and swelling of the skin that resembles
severe burns (toxic epidermal necrolysis), severe form of skin rash with flushing, fever, blisters or ulcers (Stevens-Johnson Syndrome), widespread skin rash – circular, irregular red patches on the skin of the hands and arms (erythema multiforme), ‘symptom complex’ which may include one or more of the following: fever, blood vessel inflammation, muscle pain (myalgia), joint pain (arthralgia) or inflammation (arthritis), blood changes (such as positive antinuclear antibodies, elevated red blood cell sedimentation rate), sensitivity to sunlight or artificial light (e.g. sun beds), or other skin reactions.
(frequency cannot be estimated from the available data): Fainting, depression.