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The product code for this leaflet is: PL 00142/0210


Amiloride Tablets BP 5mg

Company Details

Actavis UK Ltd

Whiddon ValleyBarnstapleDevonEX32 8NS
Medical Information Direct Line:
Medical Information
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Amiloride 5mg tablets

Read all of this leaflet carefully before you start taking this medicine.

  • Keep this leaflet. You may need to read it again.
  • If you have any further questions, ask your doctor or pharmacist.
  • This medicine has been prescribed for you. Do not pass it on to others. It may harm them even if their symptoms are the same as yours.


1 What Amiloride tablets are and what they are used for
2 Before you take
3 How to take
4 Possible side effects
5 How to store
6 Further information

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1 What Amiloride tablets are and what they are used for

Amiloride tablets belong to a group of medicines called diuretics (water tablets). Amiloride tablets can be used on their own (monotherapy) or with other drugs such as thiazide diuretics.

They may be used for:

  • high blood pressure
  • congestive heart failure
  • liver cirrhosis with swelling of the abdomen (ascites).
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2 Before you take

Do not take Amiloride tablets and tell your doctor if you are:

  • allergic (hypersensitive) to amiloride hydrochloride or any of the other ingredients in Amiloride tablets or (see section 6).
  • giving the tablets to a child
  • taking any potassium conserving drugs or potassium supplements
  • not producing any urine
  • pregnant or breastfeeding.

or if you have:

  • high blood levels of potassium (hyperkalaemia)
  • severe kidney disease or kidney failure
  • diabetic neuropathy (diabetic nerve damage causing pain, weakness or numbness).

Check with your doctor or pharmacist before taking Amiloride tablets if you:

  • have or have had high levels of acid in the body (metabolic or respiratory acidosis) caused by heart disease
  • have severe liver disease
  • have kidney impairment
  • have disturbances of blood chemicals
  • are elderly.

Taking other medicines

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Especially:

  • lithium (for some mental illnesses)
  • antidiabetic drugs such as chlorpropamide
  • ciclosporin and tacrolimus (used in rheumatism, psoriasis and to prevent organ rejection)
  • medicines for high blood pressure such as ACE inhibitors (captopril or enalapril), Angiotensin II antagonists (losartan, valsartan), beta blockers (sotolol), calcium channel blockers (amlodipine, diltiazem), adrenergic neurone blockers, alphablockers (prazosin), clonidine, diazoxide, methyldopa, moxonidine, hydralazine, minoxidil and sodium nitroprusside
  • non-steroidal anti-inflammatory drugs (NSAIDs) for pain e.g. ibuprofen or naproxen
  • antidepressants such as MAOIs, tricyclics, St Johns Wort
  • carbamazepine (used in epilepsy)
  • aldesleukin and trilostane (used in certain cancers)
  • general anaesthetic
  • antipsychotics such as amisulpride and pimozide, phenothiazines such as chlorpromazine or anxiolytics and hypnotics such as diazepam (used in mental illness)
  • atomoxetine (used to treat ADHD)
  • corticosteroids used to reduce inflammation
  • levodopa (used in Parkinson’s disease)
  • moxisylyte (used in Raynaud’s syndrome)
  • muscle relaxants such as baclofen and tizanidine
  • nitrates (used for certain heart conditions)
  • oestrogen and drospirenone (contraception (female hormones))
  • alprostidil (used for erectile dysfunction)
  • potassium salts

Pregnancy and breast-feeding

The use of Amiloride tablets is not recommended in pregnant women. Contact your doctor before breast feeding as you should either not breast feed or stop taking Amiloride tablets.

Driving and using machines

If you feel dizzy while taking Amiloride Tablets do not drive or operate dangerous machinery.

Sugar intolerance

If you have been told you have an intolerance to some sugars, contact your doctor before taking this medicine, as it contains a type of sugar called lactose.

Diabetic tests

If you are to be tested for diabetes or need to have other tests related to diabetes, tell your doctor you are taking Amiloride tablets. The tablets may need to be stopped at least three days before the test, as they can interfere with the results.

Taking food and drink

Avoid alcohol when taking this medicine, your blood pressure may drop too much.

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3 How to take

Always take Amiloride tablets exactly as your doctor has told you. If you are not sure, check with your doctor or pharmacist.

Swallow the tablets.



Two tablets a day either as a single or divided dose, to a maximum of four tablets a day and then gradually reduced to a maintenance dose.

High blood pressure:

One to two tablets a day up to four tablets a day.

Congestive heart failure:

One to two tablets a day up to four tablets a day and then gradually reduced to a maintenance dose.

Liver cirrhosis with swelling of the abdomen (ascites):

One tablet initially up to four tablets and then gradually reduced to a maintenance dose.


The dosage will depend on your kidney function, blood chemical levels and response to treatment. If you are elderly, it is particularly important to take this medicine exactly as prescribed.


Not recommended.

If you take more than you should

If you (or someone else) swallow a lot of tablets at the same time, or you think a child may have swallowed any, contact your nearest hospital casualty department or tell your doctor immediately. Symptoms of an overdose include dehydration and changes in the levels of certain chemicals in the blood.

If you forget to take the tablets

If you forget to take a dose take it as soon as you remember it and then take the next dose at the right time. Do not take a double dose to make up for a forgotten dose.

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4 Possible side effects

Like all medicines, Amiloride tablets can cause side effects, although not everybody gets them.

Stop taking this medicine and go to your nearest Accident and Emergency department or contact your doctor immediately if you get any of the following signs of an allergic reaction:

  • swelling of the face, lips, tongue or throat, difficulty in swallowing or breathing or a skin rash

Please tell your doctor or pharmacist if you notice any of the following side effects, they get worse or if you notice anything not listed.

  • Metabolism: changes in levels of body chemicals (increased blood potassium or decreased blood sodium).
  • Nervous system: depression, difficulty sleeping or sleepiness, confusion, nervousness, dizziness, pins and needles, feeling of spinning (vertigo), tremors and brain disease (characterised by poor concentration, confusion and delirium).
  • Heart: chest pain (angina), irregular (arrhythmia) or pounding (palpitation) heart beats, dizziness on standing due to low blood pressure, heart block.
  • Breathing: cough, difficulty breathing.
  • Stomach and intestines: stomach pain or bleeding, indigestion, wind, loss of appetite, thirst, constipation, diarrhoea, feeling or being sick, dry mouth.
  • Liver and pancreas: jaundice (yellow skin or eyes).
  • Skin: skin rash, itching, hair loss.
  • Muscles and joints: joint pain, muscle cramps, gout.
  • Urinary and genital: pain on passing water, frequent or copious water production, bladder spasms, decreased desire for sex and inability to maintain an erection.
  • Senses: stuffy nose, ringing in the ears, increased pressure in the eyes, visual disturbances.
  • Other: back, chest, neck and shoulder pain, pain in the hands and feet, tiredness, weakness, headache.

Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at:

By reporting side effects you can help provide more information on the safety of this medicine.

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5 How to store

Keep out of the reach and sight of children.

Store below 25°C in a dry place. Protect from light

Do not use Amiloride after the expiry date stated on the label/carton/bottle. The expiry date refers to the last day of that month.

Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

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6 Further information

What Amiloride tablets contain

  • Each tablet contains the active substance (the ingredient that makes the tablets work) amiloride hydrochloride (equivalent to 5mg anhydrous amiloride hydrochloride).
  • The other ingredients are lactose, magnesium stearate, maize starch, microcrystalline cellulose (E460), iron oxide yellow (E172).

What Amiloride tablets look like and contents of the pack

Amiloride tablets are yellow, uncoated tablets.

Pack size is 28.

Marketing Authorisation Holder and Manufacturer

EX32 8NS
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This leaflet was last revised in September 2015

EX32 8NS

50871200 AAAI2848

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